Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndro...
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in lamin A (encoded by
LMNA
), one of the major architectural elements of the mammalian cell nucleus
1
,
2
,
3
,
4
. The HGPS mutation activates an aberrant cryptic splice site in
LMNA
pre-mRN...
Alternative Titles
Full title
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1351119
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1351119
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1204
