Neurons Produce Type I Interferon during Viral Encephalitis
Neurons Produce Type I Interferon during Viral Encephalitis
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Type I interferons, also referred to as IFN-α/β, form the first line of defense against viral infections. Major IFN-α/β producers in the periphery are the plasmacytoid dendritic cells (pDCs). Constitutive expression of the IFN regulatory factor (IRF)-7 enables pDCs to rapidly synthesize large amounts of IFN-α/β after viral infection. In the central...
Alternative Titles
Full title
Neurons Produce Type I Interferon during Viral Encephalitis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1458506
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1458506
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0602460103
