Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alter...
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
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Author / Creator
Dorrance, Adrienne M , Liu, Shujun , Yuan, Weifeng , Becknell, Brian , Arnoczky, Kristy J , Guimond, Martin , Strout, Matthew P , Feng, Lan , Nakamura, Tatsuya , Yu, Li , Rush, Laura J , Weinstein, Michael , Leone, Gustavo , Wu, Lizhao , Ferketich, Amy , Whitman, Susan P , Marcucci, Guido and Caligiuri, Michael A
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
We previously identified a rearrangement of mixed-lineage leukemia (MLL) gene (also known as ALL-1, HRX, and HTRX1), consisting of an in-frame partial tandem duplication (PTD) of exons 5 through 11 in the absence of a partner gene, occurring in approximately 4%-7% of patients with acute myeloid leukemia (AML) and normal cytogenetics, and associated...
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Full title
Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1564428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1564428
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/jci25546
