Pressor and pulmonary responses to ET‐1(1–31) in guinea‐pigs
Pressor and pulmonary responses to ET‐1(1–31) in guinea‐pigs
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Contents
Endothelin‐1(1–31) (ET‐1(1–31); 0.25 to 4 nmol kg−1; i.v.) induced, in the guinea‐pig, graded increases in MAP and an indomethacin‐sensitive enhancement of pulmonary insufflation pressure (PIP). At all doses, ET‐1(1–31) induced a monophasic pressor response, except at 4 nmol kg−1, which caused a rapid and transient response (first phase: over first...
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Full title
Pressor and pulmonary responses to ET‐1(1–31) in guinea‐pigs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573412
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573412
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0704782