Interleukin‐1β inhibits ATP‐induced protein kinase B activation in renal mesangial cells by two diff...
Interleukin‐1β inhibits ATP‐induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide
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Oxford, UK: Blackwell Publishing Ltd
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English
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Oxford, UK: Blackwell Publishing Ltd
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Extracellular nucleotides, like ATP and UTP, have been shown to activate the protein kinase B (PKB) pathway in mesangial cells. In this study we report that the pro‐inflammatory cytokine interleukin‐1β (IL‐1β) inhibits ATP‐induced PKB activation.
Pretreatment of mesangial cells with IL‐1β leads to a time‐dependent decrease of ATP‐induced PKB pho...
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Full title
Interleukin‐1β inhibits ATP‐induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573688
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1573688
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ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0705064
