p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration
p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Internalization and proteolytic degradation of epidermal growth factor (EGF) receptor (R) following ligand binding is an important mechanism for regulating EGF‐stimulated signals. Using pharmacological and RNA interference inhibition of p38 mitogen‐activated protein kinase, we show that p38 is required for efficient EGF‐induced EGFR destruction but...
Alternative Titles
Full title
p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1698902
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1698902
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/sj.emboj.7601457
