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Molecular Determinants of the Functional Interaction between Syntaxin and N-Type Ca2+Channel Gating

Molecular Determinants of the Functional Interaction between Syntaxin and N-Type Ca2+Channel Gating

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_17680

Molecular Determinants of the Functional Interaction between Syntaxin and N-Type Ca2+Channel Gating

About this item

Full title

Molecular Determinants of the Functional Interaction between Syntaxin and N-Type Ca2+Channel Gating

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (25), p.13943-13948

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

Syntaxin is a key presynaptic protein that binds to N- and P/Q-type Ca2+channels in biochemical studies and affects gating of these Ca2+channels in expressionsystems and in synaptosomes. The present study was aimed at understanding the molecular basis of syntaxin modulation of N-type channel gating. Mutagenesis of either syntaxin 1A or the pore-for...

Alternative Titles

Full title

Molecular Determinants of the Functional Interaction between Syntaxin and N-Type Ca2+Channel Gating

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_17680

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_17680

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.220389697

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