Cervical Epithelial Cells Transduced with the Papillomavirus E6/E7 Oncogenes Maintain Stable Levels...
Cervical Epithelial Cells Transduced with the Papillomavirus E6/E7 Oncogenes Maintain Stable Levels of Oncoprotein Expression but Exhibit Progressive, Major Increases in hTERT Gene Expression and Telomerase Activity
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Bethesda, MD: Elsevier Inc
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English
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Bethesda, MD: Elsevier Inc
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Cervical carcinoma cells display high telomerase activity and usually contain and express integrated copies of the human papillomavirus (HPV) genome. Recent studies have demonstrated that the E6 oncogene of malignancy-associated HPVs increases cellular telomerase activity, predominantly via transcriptional activation of the catalytic subunit of tel...
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Full title
Cervical Epithelial Cells Transduced with the Papillomavirus E6/E7 Oncogenes Maintain Stable Levels of Oncoprotein Expression but Exhibit Progressive, Major Increases in hTERT Gene Expression and Telomerase Activity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1867234
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1867234
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ISSN
0002-9440
E-ISSN
1525-2191
DOI
10.1016/S0002-9440(10)62552-7