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Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1885616

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

About this item

Full title

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (21), p.8995-9000

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Chromosome instability and aneuploidy are hallmarks of cancer, but it is not clear how changes in the chromosomal content of a cell contribute to the malignant phenotype. Previously we have shown that we can readily isolate highly proliferative tumor cells and their revertants from highly invasive tumor cell populations, indicating how phenotypic s...

Alternative Titles

Full title

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1885616

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1885616

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0700631104

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