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Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1894777

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

About this item

Full title

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2007-06, Vol.26 (12), p.2915-2922

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Germline mutations in
BRCA2
predispose to hereditary breast cancers. BRCA2 protein regulates recombinational repair by interaction with RAD51 via a series of degenerate BRC repeat motifs encoded by exon 11 (BRCA2
996–2113
), and an unrelated C‐terminal domain (BRCA2
3265–3330
). BRCA2 is also required for meiotic recombination. He...

Alternative Titles

Full title

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1894777

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1894777

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/sj.emboj.7601739

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