AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
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Author / Creator
Claret, Marc , Smith, Mark A , Batterham, Rachel L , Selman, Colin , Choudhury, Agharul I , Fryer, Lee G D , Clements, Melanie , Al-Qassab, Hind , Heffron, Helen , Xu, Allison W , Speakman, John R , Barsh, Gregory S , Viollet, Benoit , Vaulont, Sophie , Ashford, Michael L J , Carling, David and Withers, Dominic J
Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Hypothalamic AMP-activated protein kinase (AMPK) has been suggested to act as a key sensing mechanism, responding to hormones and nutrients in the regulation of energy homeostasis. However, the precise neuronal populations and cellular mechanisms involved are unclear. The effects of long-term manipulation of hypothalamic AMPK on energy balance are...
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Full title
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1934578
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1934578
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI31516