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Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atheroscleros...

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atheroscleros...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2066200

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

About this item

Full title

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.3900-3908

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

HDLs protect against the development of atherosclerosis, but the underlying mechanisms are poorly understood. HDL and its apolipoproteins can promote cholesterol efflux from macrophage foam cells via the ATP-binding cassette transporters ABCA1 and ABCG1. Experiments addressing the individual roles of ABCA1 and ABCG1 in the development of atheroscle...

Alternative Titles

Full title

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2066200

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2066200

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/jci33372

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