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IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mamma...

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mamma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2096439

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

About this item

Full title

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.3988-4002

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

Subjects

Subjects and topics

More information

Scope and Contents

Contents

High serum levels of IL-6 correlate with poor outcome in breast cancer patients. However, no data are available on the relationship between IL-6 and mammary stem/progenitor cells, which may fuel the genesis of breast cancer in vivo. Herein, we address this issue in the MCF-7 breast cancer cell line and in primary human mammospheres (MS), multicellu...

Alternative Titles

Full title

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2096439

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2096439

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI32533

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