Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in...
Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes
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Publisher
American Society for Clinical Investigation
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Language
English
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American Society for Clinical Investigation
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Phosphatidylinositol-4,5-bisphosphate ([PIP.sub.2]) is an abundant phospholipid that contributes to second messenger formation and has also been shown to contribute to the regulation of cytoskeletal dynamics in all eukaryotic cells. Although the α, β, and γ isoforms of phosphatidylinositol-4-phosphate-5-kinase I (PIP5KI) all synthesize PIP2, mammal...
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Full title
Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2176194
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2176194
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ISSN
0021-9738
DOI
10.1172/JCI34239
