Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Akt kinases control essential cellular functions, including proliferation, apoptosis, metabolism and transcription, and have been proposed as promising targets for treatment of angiogenesis-dependent pathologies, such as cancer and ischemic injury. But their precise roles in neovascularization remain elusive. Here we show that Akt1 is the predomina...
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Full title
Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2277080
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2277080
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1307