Log in to save to my catalogue

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2277080

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

About this item

Full title

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2005-11, Vol.11 (11), p.1188-1196

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Akt kinases control essential cellular functions, including proliferation, apoptosis, metabolism and transcription, and have been proposed as promising targets for treatment of angiogenesis-dependent pathologies, such as cancer and ischemic injury. But their precise roles in neovascularization remain elusive. Here we show that Akt1 is the predomina...

Alternative Titles

Full title

Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2277080

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2277080

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1307

How to access this item