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Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361129

Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

About this item

Full title

Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

Publisher

Boston, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2008-03, Vol.358 (11), p.1109-1117

Language

English

Formats

Publication information

Publisher

Boston, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

Immediate hypersensitivity reactions to the monoclonal antibody cetuximab, used for the treatment of colorectal cancer and cancer of the head and neck, were found to be associated with IgE antibodies against cetuximab. These antibodies were present in pretreatment serum and were specific for galactose-α-1,3-galactose on the heavy chain of the cetux...

Alternative Titles

Full title

Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-α-1,3-Galactose

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361129

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361129

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa074943

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