Gene expression signatures for colorectal cancer microsatellite status and HNPCC
Gene expression signatures for colorectal cancer microsatellite status and HNPCC
About this item
Full title
Author / Creator
Kruhøffer, M , Jensen, J L , Laiho, P , Dyrskjøt, L , Salovaara, R , Arango, D , Birkenkamp-Demtroder, K , Sørensen, F B , Christensen, L L , Buhl, L , Mecklin, J-P , Järvinen, H , Thykjaer, T , Wikman, F P , Bech-Knudsen, F , Juhola, M , Nupponen, N N , Laurberg, S , Andersen, C L , Aaltonen, L A and Ørntoft, T F
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The majority of microsatellite instable (MSI) colorectal cancers are sporadic, but a subset belongs to the syndrome hereditary nonpolyposis colorectal cancer (HNPCC). Microsatellite instability is caused by dysfunction of the mismatch repair (MMR) system that leads to a mutator phenotype, and MSI is correlated to prognosis and response to chemother...
Alternative Titles
Full title
Gene expression signatures for colorectal cancer microsatellite status and HNPCC
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2361815
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/sj.bjc.6602621
