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Increased risk of cancer in patients with fumarate hydratase germline mutation
Author / Creator:Lehtonen, H J ; Kiuru, M ; Ylisaukko-oja, S K ; Salovaara, R ; Herva, R ; Koivisto, P A ; Vierimaa, O ; Aittomäki, K ; Pukkala, E ; Launonen, V ; Aaltonen, L A
Publisher:London: BMJ Publishing Group Ltd
Journal title:Journal of medical genetics, 2006-06, Vol.43 (6), p.523-526
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Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis
Author / Creator:Laiho, P ; Kokko, A ; Vanharanta, S ; Salovaara, R ; Sammalkorpi, H ; Järvinen, H ; Mecklin, J-P ; Karttunen, T J ; Tuppurainen, K ; Davalos, V ; Schwartz, S ; Arango, D ; Mäkinen, M J ; Aaltonen, L A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2007-01, Vol.26 (2), p.312-320
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Frequent loss of SMAD4/DPC4 protein in colorectal cancers
Author / Creator:Salovaara, R ; Roth, S ; Loukola, A ; Launonen, V ; Sistonen, P ; Avizienyte, E ; Kristo, P ; Järvinen, H ; Souchelnytskyi, S ; Sarlomo-Rikala, M ; Aaltonen, L A
Publisher:London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2002-07, Vol.51 (1), p.56-59
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Gene expression signatures for colorectal cancer microsatellite status and HNPCC
Author / Creator:Kruhøffer, M ; Jensen, J L ; Laiho, P ; Dyrskjøt, L ; Salovaara, R ; Arango, D ; Birkenkamp-Demtroder, K ; Sørensen, F B ; Christensen, L L ; Buhl, L ; Mecklin, J-P ; Järvinen, H ; Thykjaer, T ; Wikman, F P ; Bech-Knudsen, F ; Juhola, M ; Nupponen, N N ; Laurberg, S ; Andersen, C L ; Aaltonen, L A ; Ørntoft, T F
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2005-06, Vol.92 (12), p.2240-2248
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No SMAD4 hypermethylation in colorectal cancer
Author / Creator:Roth, S ; Laiho, P ; Salovaara, R ; Launonen, V ; Aaltonen, L A
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2000-10, Vol.83 (8), p.1015-1019
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E-cadherin is not frequently mutated in hereditary gastric cancer
Author / Creator:AVIZIENYTE, Egle ; LAUNONEN, Virpi ; SALOVAARA, Reijo ; KIVILUOTO, Tuula ; AALTONEN, Lauri A
Publisher:London: BMJ
Journal title:Journal of medical genetics, 2001, Vol.38 (1), p.49-52
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The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study
Author / Creator:Müller, W ; Burgart, L J ; Krause-Paulus, R ; Thibodeau, S N ; Almeida, M ; Edmonston, T B ; Boland, C R ; Sutter, C ; Jass, J R ; Lindblom, A ; Lubinski, J ; MacDermot, K ; Sanders, D S ; Morreau, H ; Müller, A ; Oliani, C ; Orntoft, T ; Ponz De Leon, M ; Rosty, C ; Rodriguez-Bigas, M ; Rüschoff, J ; Ruszkiewicz, A ; Sabourin, J ; Salovaara, R ; Möslein, G
Publisher:Netherlands: Springer Nature B.V
Journal title:Familial cancer, 2001, Vol.1 (2), p.87
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Sudden death due to rupture of the arteria pancreatica magna: a complication of an immature pseudocyst in chronic pancreatitis
Author / Creator:Lunetta, P. ; Penttilä, A. ; Salovaara, R. ; Sajantila, A.
Publisher:Germany: Springer Nature B.V
Journal title:International journal of legal medicine, 2002-02, Vol.116 (1), p.43-46
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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
Author / Creator:Tomlinson, Ian P M ; Alam, N Afrina ; Rowan, Andrew J ; Barclay, Ella ; Jaeger, Emma E M ; Kelsell, David ; Leigh, Irene ; Gorman, Patricia ; Lamlum, Hanan ; Rahman, Shamima ; Roylance, Rebecca R ; Olpin, Simon ; Bevan, Stephen ; Barker, Karen ; Hearle, Nicholas ; Houlston, Richard S ; Kiuru, Maija ; Lehtonen, Rainer ; Karhu, Auli ; Vilkki, Susa ; Laiho, Päivi ; Eklund, Carita ; Vierimaa, Outi ; Aittomäki, Kristiina ; Hietala, Marja ; Sistonen, Pertti ; Paetau, Anders ; Salovaara, Reijo ; Herva, Riitta ; Launonen, Virpi ; Aaltonen, Lauri A
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2002-04, Vol.30 (4), p.406-410
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Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease
Author / Creator:Aaltonen, Lauri A ; Salovaara, Reijo ; Kristo, Paula ; Canzian, Federico ; Hemminki, Akseli ; Peltomäki, Päivi ; Chadwick, Robert B ; Kääriäinen, Helena ; Eskelinen, Matti ; Järvinen, Heikki ; Mecklin, Jukka-Pekka ; de la Chapelle, Albert ; Percesepe, Antonio ; Ahtola, Heikki ; Härkönen, Niilo ; Julkunen, Risto ; Kangas, Eero ; Ojala, Seppo ; Tulikoura, Jukka ; Valkamo, Erkki
Publisher:Boston, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 1998-05, Vol.338 (21), p.1481-1487
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A serine/threonine kinase gene defective in Peutz–Jeghers syndrome
Author / Creator:Hemminki, Akseli ; Markie, David ; Tomlinson, Ian ; Avizienyte, Egle ; Roth, Stina ; Loukola, Anu ; Bignell, Graham ; Warren, William ; Aminoff, Maria ; Höglund, Pia ; Järvinen, Heikki ; Kristo, Paula ; Pelin, Katarina ; Ridanpää, Maaret ; Salovaara, Reijo ; Toro, Tumi ; Bodmer, Walter ; Olschwang, Sylviane ; Olsen, Anne S. ; Stratton, Michael R. ; de la Chapelle, Albert ; Aaltonen, Lauri A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1998-01, Vol.391 (6663), p.184-187
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PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers
Author / Creator:Zhou, Xiao-Ping ; Loukola, Anu ; Salovaara, Reijo ; Nystrom-Lahti, Minna ; Peltomäki, Päivi ; de la Chapelle, Albert ; Aaltonen, Lauri A. ; Eng, Charis
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2002-08, Vol.161 (2), p.439-447
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Familial Cutaneous Leiomyomatosis Is a Two-Hit Condition Associated with Renal Cell Cancer of Characteristic Histopathology
Author / Creator:Kiuru, Maija ; Launonen, Virpi ; Hietala, Marja ; Aittomäki, Kristiina ; Vierimaa, Outi ; Salovaara, Reijo ; Arola, Johanna ; Pukkala, Eero ; Sistonen, Pertti ; Herva, Riitta ; Aaltonen, Lauri A.
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2001-09, Vol.159 (3), p.825-829
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Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers
Author / Creator:Kuismanen, Shannon A. ; Holmberg, Mari T. ; Salovaara, Reijo ; de la Chapelle, Albert ; Peltomäki, Päivi
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2000-05, Vol.156 (5), p.1773-1779
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Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability
Author / Creator:Kuismanen, Shannon A. ; Moisio, Anu-Liisa ; Schweizer, Pascal ; Truninger, Kaspar ; Salovaara, Reijo ; Arola, Johanna ; Butzow, Ralf ; Jiricny, Josef ; Nyström-Lahti, Minna ; Peltomäki, Päivi
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2002-06, Vol.160 (6), p.1953-1958
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Induction of Cyclooxygenase-2 in a Mouse Model of Peutz-Jeghers Polyposis
Author / Creator:Rossi, Derrick J. ; Ylikorkala, Antti ; Korsisaari, Nina ; Salovaara, Reijo ; Luukko, Keijo ; Launonen, Virpi ; Henkemeyer, Mark ; Ristimäki, Ari ; Aaltonen, Lauri A. ; Mäkelä, Tomi P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12327-12332
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Genetic Reconstruction of Individual Colorectal Tumor Histories
Author / Creator:Tsao, Jen-Lan ; Yatabe, Yasushi ; Salovaara, Reijo ; Jarvinen, Heikki J. ; Mecklin, Jukka-Pekka ; Aaltonen, Lauri A. ; Tavare, Simon ; Shibata, Darryl
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (3), p.1236-1241
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Epigenetic Phenotypes Distinguish Microsatellite-Stable and -Unstable Colorectal Cancers
Author / Creator:Kuismanen, Shannon A. ; Holmberg, Mari T. ; Salovaara, Reijo ; Schweizer, Pascal ; Aaltonen, Lauri A. ; de la Chapelle, Albert ; Nyström-Lahti, Minna ; Peltomäki, Päivi
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12661-12666
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LKB1 Somatic Mutations in Sporadic Tumors
Author / Creator:Avizienyte, Egle ; Loukola, Anu ; Roth, Stina ; Hemminki, Akseli ; Tarkkanen, Maija ; Salovaara, Reijo ; Arola, Johanna ; Bützow, Ralf ; Husgafvel-Pursiainen, Kirsti ; Kokkola, Arto ; Järvinen, Heikki ; Aaltonen, Lauri A.
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 1999-03, Vol.154 (3), p.677-681
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Allelic Analysis of Serous Ovarian Carcinoma Reveals Two Putative Tumor Suppressor Loci at 18q22-q23 Distal to SMAD4, SMAD2, and DCC
Author / Creator:Lassus, Heini ; Salovaara, Reijo ; Aaltonen, Lauri A. ; Butzow, Ralf
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2001-07, Vol.159 (1), p.35-42
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Showing 1 to 20 of 36 results

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Increased risk of cancer in patients with fumarate hydratase germline mutation

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Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis

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Frequent loss of SMAD4/DPC4 protein in colorectal cancers

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Gene expression signatures for colorectal cancer microsatellite status and HNPCC

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No SMAD4 hypermethylation in colorectal cancer

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E-cadherin is not frequently mutated in hereditary gastric cancer

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The reliability of immunohistochemistry as a prescreening method for the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC)--results of an international collaborative study

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Sudden death due to rupture of the arteria pancreatica magna: a complication of an immature pseudocyst in chronic pancreatitis

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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

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Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

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A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

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PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers

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Familial Cutaneous Leiomyomatosis Is a Two-Hit Condition Associated with Renal Cell Cancer of Characteristic Histopathology

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Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers

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Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

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Induction of Cyclooxygenase-2 in a Mouse Model of Peutz-Jeghers Polyposis

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Genetic Reconstruction of Individual Colorectal Tumor Histories

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Epigenetic Phenotypes Distinguish Microsatellite-Stable and -Unstable Colorectal Cancers

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LKB1 Somatic Mutations in Sporadic Tumors

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Allelic Analysis of Serous Ovarian Carcinoma Reveals Two Putative Tumor Suppressor Loci at 18q22-q23 Distal to SMAD4, SMAD2, and DCC

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