Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of...
Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2
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Author / Creator
Publisher
Boston: Boston : Springer US
Journal title
Language
English
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Publication information
Publisher
Boston: Boston : Springer US
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Scope and Contents
Contents
We reported previously that Fas-induced hepatic failure in normal mice was attenuated or prevented by exogenous transferrin (Tf), particularly apoTf. Here we show in C57BL6J/129 mice with genetic inactivation of transferrin receptor 2 (TfR2Y²⁴⁵X), that Fas-induced hepatotoxicity (apoptosis; rise in plasma aspartate aminotransferase (AST) levels) wa...
Alternative Titles
Full title
Transferrin fails to provide protection against Fas-induced hepatic injury in mice with deletion of functional transferrin-receptor type 2
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574612
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2574612
Other Identifiers
ISSN
1360-8185
E-ISSN
1573-675X
DOI
10.1007/s10495-008-0233-6
