Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal...
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Cancers are clonal expansions, but how a single, transformed human cell grows into a billion-cell tumor is uncertain because serial observations are impractical. Potentially, this history is surreptitiously recorded within genomes that become increasingly numerous, polymorphic, and physically separated after transformation. To correlate physical wi...
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Full title
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2651202
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2651202
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0810276106