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Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal...

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2651202

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers

About this item

Full title

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (12), p.4828-4833

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Cancers are clonal expansions, but how a single, transformed human cell grows into a billion-cell tumor is uncertain because serial observations are impractical. Potentially, this history is surreptitiously recorded within genomes that become increasingly numerous, polymorphic, and physically separated after transformation. To correlate physical wi...

Alternative Titles

Full title

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2651202

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2651202

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0810276106

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