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The Fas–FADD death domain complex structure unravels signalling by receptor clustering

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2661029

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

About this item

Full title

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2009-02, Vol.457 (7232), p.1019-1022

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The complexities of cell death
The crystal structure of a complex between the cell surface receptor protein Fas and the Fas-associated death domain (FADD) protein - a central feature of the so-called death-inducing signalling complex of apoptosis-inducing cellular receptors - has been determined at 2.7 Å resolution. The structure reveals a previ...

Alternative Titles

Full title

The Fas–FADD death domain complex structure unravels signalling by receptor clustering

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2661029

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2661029

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature07606