Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-n...
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
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Author / Creator
Caldas-Lopes, Eloisi , Cerchietti, Leandro , Ahn, James H , Clement, Cristina C , Robles, Ana I , Rodina, Anna , Moulick, Kamalika , Taldone, Tony , Gozman, Alexander , Guo, Yunke , Wu, Nian , de Stanchina, Elisa , White, Julie , Gross, Steven S , Ma, Yuliang , Varticovski, Lyuba , Melnick, Ari and Chiosis, Gabriela
Publisher
United States: National Acad Sciences
Journal title
Language
English
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Publisher
United States: National Acad Sciences
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Scope and Contents
Contents
Triple-negative breast cancers (TNBCs) are defined by a lack of expression of estrogen, progesterone, and HER2 receptors. Because of the absence of identified targets and targeted therapies, and due to a heterogeneous molecular presentation, treatment guidelines for patients with TNBC include only conventional chemotherapy. Such treatment, while ef...
Alternative Titles
Full title
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2688867
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2688867
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0903392106