Transmission and spreading of tauopathy in transgenic mouse brain
Transmission and spreading of tauopathy in transgenic mouse brain
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Intracellular tau inclusions, a hallmark of several neurodegenerative diseases, propagate in the brain in an unknown fashion. Brain extracts prepared from mice expressing mutated human tau injected into mice expressing wild-type human tau induce the formation and spread of wild-type human tau inclusions.
Hyperphosphorylated tau makes up the fila...
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Transmission and spreading of tauopathy in transgenic mouse brain
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2726961
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2726961
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/ncb1901