cAMP-Dependent Signaling as a Core Component of the Mammalian Circadian Pacemaker
cAMP-Dependent Signaling as a Core Component of the Mammalian Circadian Pacemaker
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
The mammalian circadian clockwork is modeled as transcriptional and posttranslational feedback loops, whereby circadian genes are periodically suppressed by their protein products. We show that adenosine 3',5'-monophosphate (cAMP) signaling constitutes an additional, bona fide component of the oscillatory network. cAMP signaling is rhythmic and sus...
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Full title
cAMP-Dependent Signaling as a Core Component of the Mammalian Circadian Pacemaker
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2735813
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2735813
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1152506
