Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Techniques for systematically monitoring protein translation have lagged far behind methods for measuring messenger RNA (mRNA) levels. Here, we present a ribosome-profiling strategy that is based on the deep sequencing of ribosome-protected mRNA fragments and enables genome-wide investigation of translation with subcodon resolution. We used this te...
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Full title
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2746483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2746483
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1168978
