Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Protein S (ProS) is a blood anticoagulant encoded by the Pros1 gene, and ProS deficiencies are associated with venous thrombosis, stroke, and autoimmunity. These associations notwithstanding, the relative risk that reduced ProS expression confers in different disease settings has been difficult to assess without an animal model. We have now describ...
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Full title
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2752078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2752078
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI39325
