Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease th...
Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERα)
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New York: Elsevier Inc
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Language
English
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New York: Elsevier Inc
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Contents
Matrix metalloproteinases (MMPs) have a crucial function in migration of inflammatory cells into the central nervous system (CNS). Levels of MMP-9 are elevated in multiple sclerosis (MS) and predict the occurrence of new active lesions on magnetic resonance imaging (MRI). This translational study aims to determine whether in vivo treatment with the...
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Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERα)
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2753699
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2753699
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/labinvest.2009.79