Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The IpaH family of
Shigella
virulence factors are E3 ubiquitin ligases that may target host proteins. Structural and functional characterization of IpaH1.4 and IpaH9.8 reveal a unique C-terminal catalytic domain that seems to have HECT-like E3 ligase activity. Together with an accompanying publication from Zhu
et al
., these data sugges...
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Full title
Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2764551
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2764551
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.1511
