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78 results for Savchenko,+Alexei

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ArticlesPeer ReviewedFull Text
An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp
Author / Creator:Ahmad, Shehryar ; Wang, Boyuan ; Walker, Matthew D. ; Tran, Hiu-Ki R. ; Stogios, Peter J. ; Savchenko, Alexei ; Grant, Robert A. ; McArthur, Andrew G. ; Laub, Michael T. ; Whitney, John C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-11, Vol.575 (7784), p.674-678
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Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics
Author / Creator:Venkatesan, Meenakshi ; Fruci, Michael ; Verellen, Lou Ann ; Skarina, Tatiana ; Mesa, Nathalie ; Flick, Robert ; Pham, Chester ; Mahadevan, Radhakrishnan ; Stogios, Peter J. ; Savchenko, Alexei
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-07, Vol.14 (1), p.4031-4031, Article 4031
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Galectin-9 binds IgM-BCR to regulate B cell signaling
Author / Creator:Cao, Anh ; Alluqmani, Nouf ; Buhari, Fatima Hifza Mohammed ; Wasim, Laabiah ; Smith, Logan K. ; Quaile, Andrew T. ; Shannon, Michael ; Hakim, Zaki ; Furmli, Hossai ; Owen, Dylan M. ; Savchenko, Alexei ; Treanor, Bebhinn
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-08, Vol.9 (1), p.3288-18, Article 3288
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A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase
Author / Creator:MacAlpine, Jessie ; Daniel-Ivad, Martin ; Liu, Zhongle ; Yano, Junko ; Revie, Nicole M. ; Todd, Robert T. ; Stogios, Peter J. ; Sanchez, Hiram ; O’Meara, Teresa R. ; Tompkins, Thomas A. ; Savchenko, Alexei ; Selmecki, Anna ; Veri, Amanda O. ; Andes, David R. ; Fidel, Paul L. ; Robbins, Nicole ; Nodwell, Justin ; Whitesell, Luke ; Cowen, Leah E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-10, Vol.12 (1), p.6151-16, Article 6151
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The evolution of substrate discrimination in macrolide antibiotic resistance enzymes
Author / Creator:Pawlowski, Andrew C. ; Stogios, Peter J. ; Koteva, Kalinka ; Skarina, Tatiana ; Evdokimova, Elena ; Savchenko, Alexei ; Wright, Gerard D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.112-12, Article 112
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Envelope stress responses defend against type six secretion system attacks independently of immunity proteins
Author / Creator:Hersch, Steven J. ; Watanabe, Nobuhiko ; Stietz, Maria Silvina ; Manera, Kevin ; Kamal, Fatima ; Burkinshaw, Brianne ; Lam, Linh ; Pun, Alexander ; Li, Meixin ; Savchenko, Alexei ; Dong, Tao G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2020-05, Vol.5 (5), p.706-714
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Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila
Author / Creator:Urbanus, Malene L ; Quaile, Andrew T ; Stogios, Peter J ; Morar, Mariya ; Rao, Chitong ; Di Leo, Rosa ; Evdokimova, Elena ; Lam, Mandy ; Oatway, Christina ; Cuff, Marianne E ; Osipiuk, Jerzy ; Michalska, Karolina ; Nocek, Boguslaw P ; Taipale, Mikko ; Savchenko, Alexei ; Ensminger, Alexander W
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2016-12, Vol.12 (12), p.893-n/a
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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy
Author / Creator:Rolando, Monica ; Escoll, Pedro ; Nora, Tamara ; Botti, Joëlle ; Boitez, Valérie ; Bedia, Carmen ; Daniels, Craig ; Abraham, Gilu ; Stogios, Peter J. ; Skarina, Tatiana ; Christophe, Charlotte ; Dervins-Ravault, Delphine ; Cazalet, Christel ; Hilbi, Hubert ; Rupasinghe, Thusitha W. T. ; Tull, Dedreia ; McConville, Malcolm J. ; Ong, Sze Ying ; Hartland, Elizabeth L. ; Codogno, Patrice ; Levade, Thierry ; Naderer, Thomas ; Savchenko, Alexei ; Buchrieser, Carmen
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1901-1906
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Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
Author / Creator:Beloglazova, Natalia ; Petit, Pierre ; Flick, Robert ; Brown, Greg ; Savchenko, Alexei ; Yakunin, Alexander F
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2011-11, Vol.30 (22), p.4616-4627
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Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections
Author / Creator:Cruz, Melissa R. ; Cristy, Shane ; Guha, Shantanu ; De Cesare, Giuseppe Buda ; Evdokimova, Elena ; Sanchez, Hiram ; Borek, Dominika ; Miramón, Pedro ; Yano, Junko ; Fidel, Paul L. ; Savchenko, Alexei ; Andes, David R. ; Stogios, Peter J. ; Lorenz, Michael C. ; Garsin, Danielle A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-10, Vol.13 (1), p.6047-6047, Article 6047
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Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans
Author / Creator:Puumala, Emily ; Nandakumar, Meganathan ; Yiu, Bonnie ; Stogios, Peter J. ; Strickland, Benjamin G. ; Zarnowski, Robert ; Wang, Xiaoyu ; Williams, Noelle S. ; Savchenko, Alexei ; Andes, David R. ; Robbins, Nicole ; Whitesell, Luke ; Willson, Timothy M. ; Cowen, Leah E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2156-16, Article 2156
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Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors
Author / Creator:Patel, Deepak T ; Stogios, Peter J ; Jaroszewski, Lukasz ; Urbanus, Malene L ; Sedova, Mayya ; Semper, Cameron ; Le, Cathy ; Takkouche, Abraham ; Ichii, Keita ; Innabi, Julie ; Patel, Dhruvin H ; Ensminger, Alexander W ; Godzik, Adam ; Savchenko, Alexei
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2025-01, Vol.21 (1), p.59-89
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Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families
Author / Creator:Popovic, Ana ; Hai, Tran ; Tchigvintsev, Anatoly ; Hajighasemi, Mahbod ; Nocek, Boguslaw ; Khusnutdinova, Anna N. ; Brown, Greg ; Glinos, Julia ; Flick, Robert ; Skarina, Tatiana ; Chernikova, Tatyana N. ; Yim, Veronica ; Brüls, Thomas ; Paslier, Denis Le ; Yakimov, Michail M. ; Joachimiak, Andrzej ; Ferrer, Manuel ; Golyshina, Olga V. ; Savchenko, Alexei ; Golyshin, Peter N. ; Yakunin, Alexander F.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.44103, Article 44103
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Addendum: A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase
Author / Creator:MacAlpine, Jessie ; Daniel-Ivad, Martin ; Liu, Zhongle ; Yano, Junko ; Revie, Nicole M. ; Todd, Robert T. ; Stogios, Peter J. ; Sanchez, Hiram ; O’Meara, Teresa R. ; Tompkins, Thomas A. ; Savchenko, Alexei ; Selmecki, Anna ; Veri, Amanda O. ; Andes, David R. ; Fidel, Paul L. ; Robbins, Nicole ; Nodwell, Justin ; Whitesell, Luke ; Cowen, Leah E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.6440-1, Article 6440
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Rifampin phosphotransferase is an unusual antibiotic resistance kinase
Author / Creator:Stogios, Peter J. ; Cox, Georgina ; Spanogiannopoulos, Peter ; Pillon, Monica C. ; Waglechner, Nicholas ; Skarina, Tatiana ; Koteva, Kalinka ; Guarné, Alba ; Savchenko, Alexei ; Wright, Gerard D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-04, Vol.7 (1), p.11343-12, Article 11343
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A Pathogen Type III Effector with a Novel E3 Ubiquitin Ligase Architecture
Author / Creator:Singer, Alexander U. ; Schulze, Sebastian ; Skarina, Tatiana ; Xu, Xiaohui ; Cui, Hong ; Eschen-Lippold, Lennart ; Egler, Monique ; Srikumar, Tharan ; Raught, Brian ; Lee, Justin ; Scheel, Dierk ; Savchenko, Alexei ; Bonas, Ulla
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2013-01, Vol.9 (1), p.e1003121-e1003121
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Structural basis for the evolution of vancomycin resistance D,D-peptidases
Author / Creator:Meziane-Cherif, Djalal ; Stogios, Peter J. ; Evdokimova, Elena ; Savchenko, Alexei ; Courvalin, Patrice
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.5872-5877
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Identification and characterization of a large family of superbinding bacterial SH2 domains
Author / Creator:Kaneko, Tomonori ; Stogios, Peter J. ; Ruan, Xiang ; Voss, Courtney ; Evdokimova, Elena ; Skarina, Tatiana ; Chung, Amy ; Liu, Xiaoling ; Li, Lei ; Savchenko, Alexei ; Ensminger, Alexander W. ; Li, Shawn S.-C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-10, Vol.9 (1), p.4549-15, Article 4549
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Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
Author / Creator:Singer, Alexander U ; Rohde, John R ; Lam, Robert ; Skarina, Tatiana ; Kagan, Olga ; DiLeo, Rosa ; Chirgadze, Nickolay Y ; Cuff, Marianne E ; Joachimiak, Andrzej ; Tyers, Mike ; Sansonetti, Philippe J ; Parsot, Claude ; Savchenko, Alexei
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2008-12, Vol.15 (12), p.1293-1301
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Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria
Author / Creator:Nocek, Boguslaw ; Kochinyan, Samvel ; Proudfoot, Michael ; Brown, Greg ; Evdokimova, Elena ; Osipiuk, Jerzy ; Edwards, Aled M ; Savchenko, Alexei ; Joachimiak, Andrzej ; Yakunin, Alexander F
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (46), p.17730-17735
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Showing 1 to 20 of 78 results

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An interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp

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Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics

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Galectin-9 binds IgM-BCR to regulate B cell signaling

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A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase

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The evolution of substrate discrimination in macrolide antibiotic resistance enzymes

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Envelope stress responses defend against type six secretion system attacks independently of immunity proteins

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Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

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Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy

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Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference

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Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections

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Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

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Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors

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Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

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Addendum: A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase

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Rifampin phosphotransferase is an unusual antibiotic resistance kinase

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A Pathogen Type III Effector with a Novel E3 Ubiquitin Ligase Architecture

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Structural basis for the evolution of vancomycin resistance D,D-peptidases

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Identification and characterization of a large family of superbinding bacterial SH2 domains

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Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

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Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria

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