Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Double life of flu virus protein
The current H1N1 strain pandemic virus is resistant to the established antiviral agents amantadine and rimantadine, which target the M2 protein, a multifunctional membrane-spanning proton channel. The structure of this channel has been a subject of some controversy, since an X-ray crystal structure of part of the...
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Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2818718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2818718
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08722
