Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral the...
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Munger
et al
. show that infection with human cytomegalovirus upregulates fatty acid biosynthesis and that pharmacological inhibition of this pathway inhibits replication of both this virus and influenza A. This approach, the first to reliably map major carbon fluxes in mammalian cells, extends the promise of metabolomics from diagnostic appl...
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Full title
Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2825756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2825756
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.1500
