The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Mutation of the von Hippel-Lindau (VHL) tumor suppressor protein at codon 200 (R200W) is associated with a disease known as Chuvash polycythemia. In addition to polycythemia, Chuvash patients have pulmonary hypertension and increased respiratory rates, although the pathophysiological basis of these symptoms is unclear. Here we sought to address thi...
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Full title
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2827942
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2827942
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI36362
