Myeloid-derived suppressor cells as regulators of the immune system
Myeloid-derived suppressor cells as regulators of the immune system
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Key Points
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells of myeloid origin.
MDSCs expand during various pathological conditions, including cancer, inflammation and trauma, and are characterized by the increased production of reactive oxygen and nitrogen species, and by arginase 1 activity.
Two subsets of...
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Full title
Myeloid-derived suppressor cells as regulators of the immune system
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2828349
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2828349
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ISSN
1474-1733,1474-1741
E-ISSN
1474-1741
DOI
10.1038/nri2506
