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Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coro...

Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2834561

Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells

About this item

Full title

Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells

Publisher

United States: Mary Ann Liebert, Inc

Journal title

Antioxidants & redox signaling, 2010-03, Vol.12 (6), p.703-712

Language

English

Formats

Publication information

Publisher

United States: Mary Ann Liebert, Inc

More information

Scope and Contents

Contents

This study explored the mechanism mediating the aggregation of membrane NADPH oxidase (NOX) subunits and subsequent activation of this enzyme in bovine coronary arterial endothelial cells (CAECs). With confocal microscopy, we found that FasL stimulated lipid rafts (LRs) clustering with NOX subunit aggregation and acid sphingomyelinase (ASM) gatheri...

Alternative Titles

Full title

Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2834561

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2834561

Other Identifiers

ISSN

1523-0864

E-ISSN

1557-7716

DOI

10.1089/ars.2009.2461

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