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Drug Delivery–mediated Control of RNA Immunostimulation

Drug Delivery–mediated Control of RNA Immunostimulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2835254

Drug Delivery–mediated Control of RNA Immunostimulation

About this item

Full title

Drug Delivery–mediated Control of RNA Immunostimulation

Publisher

United States: Elsevier Inc

Journal title

Molecular therapy, 2009-09, Vol.17 (9), p.1555-1562

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

RNA interference (RNAi) has generated significant interest as a strategy to suppress viral infection, but in some cases antiviral activity of unmodified short-interfering RNA (siRNA) has been attributed to activation of innate immune responses. We hypothesized that immunostimulation by unmodified siRNA could mediate both RNAi as well as innate immu...

Alternative Titles

Full title

Drug Delivery–mediated Control of RNA Immunostimulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2835254

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2835254

Other Identifiers

ISSN

1525-0016

E-ISSN

1525-0024

DOI

10.1038/mt.2009.147

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