The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls
The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Nonviral gene complexes can enter mammalian cells through different endocytic pathways. For efficient optimization of the gene carrier it is important to profile its cellular uptake, because this largely determines its intracellular processing and subsequent transfection efficiency. Most of the current information on uptake of these gene-delivery v...
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Full title
The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2839427
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2839427
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2009.281