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Identifying single-cell molecular programs by stochastic profiling

Identifying single-cell molecular programs by stochastic profiling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2849806

Identifying single-cell molecular programs by stochastic profiling

About this item

Full title

Identifying single-cell molecular programs by stochastic profiling

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2010-04, Vol.7 (4), p.311-317

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

By stochastically sampling cells in groups of ten, the authors identify transcriptional programs with strong cell-to-cell expression differences thus allowing them to study endogenous heterogeneities in single cells.
Cells in tissues can be morphologically indistinguishable yet show molecular expression patterns that are remarkably heterogeneous...

Alternative Titles

Full title

Identifying single-cell molecular programs by stochastic profiling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2849806

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2849806

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/nmeth.1442

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