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Zscan4 regulates telomere elongation and genomic stability in ES cells

Zscan4 regulates telomere elongation and genomic stability in ES cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2851843

Zscan4 regulates telomere elongation and genomic stability in ES cells

About this item

Full title

Zscan4 regulates telomere elongation and genomic stability in ES cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-04, Vol.464 (7290), p.858-863

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Exceptional genomic stability is one of the hallmarks of mouse embryonic stem (ES) cells. However, the genes contributing to this stability remain obscure. We previously identified
Zscan4
as a specific marker for two-cell embryo and ES cells. Here we show that
Zscan4
is involved in telomere maintenance and long-term genomic stability in...

Alternative Titles

Full title

Zscan4 regulates telomere elongation and genomic stability in ES cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2851843

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2851843

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature08882

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