Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Scope and Contents
Contents
When internalized receptors and other cargo are destined for lysosomal degradation, they are ubiquitinated and sorted by the endosomal sorting complex required for transport (ESCRT) complexes 0, I, II and III into multivesicular bodies. Multivesicular bodies are formed when cargo-rich patches of the limiting membrane of endosomes bud inwards by an...
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Full title
Molecular mechanism of multivesicular body biogenesis by ESCRT complexes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2851844
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2851844
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08849
