Arsenite Suppresses Notch1 Signaling in Human Keratinocytes
Arsenite Suppresses Notch1 Signaling in Human Keratinocytes
About this item
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Author / Creator
Publisher
New York, NY: Elsevier Inc
Journal title
Language
English
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Publisher
New York, NY: Elsevier Inc
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More information
Scope and Contents
Contents
Arsenic is a well-known human skin carcinogen whose mechanism of action remains to be elucidated. In this work using cultured human epidermal cells, arsenite suppressed accumulation of the transcriptionally active intracellular domain of Notch1. The cells responded to an active peptide from the Notch1 ligand, Jagged1, with increased levels of diffe...
Alternative Titles
Full title
Arsenite Suppresses Notch1 Signaling in Human Keratinocytes
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2875141
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2875141
Other Identifiers
ISSN
0022-202X
E-ISSN
1523-1747
DOI
10.1038/jid.2008.207
