Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
About this item
Full title
Author / Creator
Palanisamy, Nallasivam , Ateeq, Bushra , Kalyana-Sundaram, Shanker , Pflueger, Dorothee , Ramnarayanan, Kalpana , Shankar, Sunita , Han, Bo , Cao, Qi , Cao, Xuhong , Suleman, Khalid , Kumar-Sinha, Chandan , Dhanasekaran, Saravana M , Chen, Ying-bei , Esgueva, Raquel , Banerjee, Samprit , LaFargue, Christopher J , Siddiqui, Javed , Demichelis, Francesca , Moeller, Peter , Bismar, Tarek A , Kuefer, Rainer , Fullen, Douglas R , Johnson, Timothy M , Greenson, Joel K , Giordano, Thomas J , Tan, Patrick , Tomlins, Scott A , Varambally, Sooryanarayana , Rubin, Mark A , Maher, Christopher A and Chinnaiyan, Arul M
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Using pair-end transcriptome sequencing, this study provides the identification of Raf pathway gene rearrangements in a small proportion of prostate and gastric cancers and in melanomas. The fusion proteins show tumorigenic potential and represent a unique activating alteration of this oncogenic pathway, which seems to be mutually exclusive from kn...
Alternative Titles
Full title
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
Authors, Artists and Contributors
Author / Creator
Ateeq, Bushra
Kalyana-Sundaram, Shanker
Pflueger, Dorothee
Ramnarayanan, Kalpana
Shankar, Sunita
Han, Bo
Cao, Qi
Cao, Xuhong
Suleman, Khalid
Kumar-Sinha, Chandan
Dhanasekaran, Saravana M
Chen, Ying-bei
Esgueva, Raquel
Banerjee, Samprit
LaFargue, Christopher J
Siddiqui, Javed
Demichelis, Francesca
Moeller, Peter
Bismar, Tarek A
Kuefer, Rainer
Fullen, Douglas R
Johnson, Timothy M
Greenson, Joel K
Giordano, Thomas J
Tan, Patrick
Tomlins, Scott A
Varambally, Sooryanarayana
Rubin, Mark A
Maher, Christopher A
Chinnaiyan, Arul M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2903732
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2903732
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2166
