Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transforma...
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Accumulating evidence points to inflammation as a promoter of carcinogenesis. MyD88 is an adaptor molecule in TLR and IL-1R signaling that was recently implicated in tumorigenesis through proinflammatory mechanisms. Here we have shown that MyD88 is also required in a cell-autonomous fashion for RAS-mediated carcinogenesis in mice in vivo and for MA...
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Full title
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2947228
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2947228
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/jci42771
