Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 rat...
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
About this item
Full title
Author / Creator
Kuperstein, Inna , Broersen, Kerensa , Benilova, Iryna , Rozenski, Jef , Jonckheere, Wim , Debulpaep, Maja , Vandersteen, Annelies , Segers-Nolten, Ine , Van Der Werf, Kees , Subramaniam, Vinod , Braeken, Dries , Callewaert, Geert , Bartic, Carmen , D'Hooge, Rudi , Martins, Ivo Cristiano , Rousseau, Frederic , Schymkowitz, Joost and De Strooper, Bart
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
The amyloid peptides Aβ
40
and Aβ
42
of Alzheimer's disease are thought to contribute differentially to the disease process. Although Aβ
42
seems more pathogenic than Aβ
40
, the reason for this is not well understood. We show here that small alterations in the Aβ
42
:Aβ
40
ratio dramatically affect the biophysic...
Alternative Titles
Full title
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
Authors, Artists and Contributors
Author / Creator
Broersen, Kerensa
Benilova, Iryna
Rozenski, Jef
Jonckheere, Wim
Debulpaep, Maja
Vandersteen, Annelies
Segers-Nolten, Ine
Van Der Werf, Kees
Subramaniam, Vinod
Braeken, Dries
Callewaert, Geert
Bartic, Carmen
D'Hooge, Rudi
Martins, Ivo Cristiano
Rousseau, Frederic
Schymkowitz, Joost
De Strooper, Bart
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2957213
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2957213
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2010.211
