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Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2964172

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT

About this item

Full title

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2010-10, Vol.29 (20), p.3459-3469

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Heat shock transcription factor 1 (HSF1) is an important regulator of protein homeostasis (proteostasis) by controlling the expression of major heat shock proteins (Hsps) that facilitate protein folding. However, it is unclear whether other proteostasis pathways are mediated by HSF1. Here, we identified novel targets of HSF1 in mammalian cells, whi...

Alternative Titles

Full title

Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2964172

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2964172

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2010.225

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