Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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AID-dependent DNA methylation in primordial germ cells
Epigenetic reprogramming including demethylation of DNA occurs in mammalian primordial germ cells (PGCs) and in early embryos, but the extent of this reprogramming and its molecular mechanisms are poorly understood. Here, DNA methylation profiling in PGCs reveals a genome-wide erasure of met...
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Full title
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2965733
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2965733
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature08829
