Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa
Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa
About this item
Full title
Author / Creator
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
The use of marrow stem cells to treat seven children with severe epidermolysis bullosa caused by loss-of-function mutations in
COL7A,
the gene encoding type VII collagen (C7), was examined. The investigators observed increases in C7 deposition, the presence of donor cells in the skin, and an amelioration of symptoms.
Loss of skin integrity...
Alternative Titles
Full title
Bone Marrow Transplantation for Recessive Dystrophic Epidermolysis Bullosa
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2967187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2967187
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0910501
