Emerging principles in protease-based drug discovery
Emerging principles in protease-based drug discovery
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The development of new protease inhibitors has proved challenging in recent years. In their Perspective, Drag and Salvesen discuss the underlying reasons for this, and how lessons learned from failures can inform future research directions in the field.
Proteases have an important role in many signalling pathways, and represent potential drug ta...
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Emerging principles in protease-based drug discovery
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2974563
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2974563
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/nrd3053