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The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progressio...

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progressio...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2993601

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

About this item

Full title

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2010-12, Vol.120 (12), p.4478-4492

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Retinoblastoma (RB; encoded by RB1) is a tumor suppressor that is frequently disrupted in tumorigenesis and acts in multiple cell types to suppress cell cycle progression. The role of RB in tumor progression, however, is poorly defined. Here, we have identified a critical role for RB in protecting against tumor progression through regulation of tar...

Alternative Titles

Full title

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2993601

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2993601

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI44239

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