Rewiring of Genetic Networks in Response to DNA Damage
Rewiring of Genetic Networks in Response to DNA Damage
About this item
Full title
Author / Creator
Bandyopadhyay, Sourav , Mehta, Monika , Kuo, Dwight , Sung, Min-Kyung , Chuang, Ryan , Jaehnig, Eric J , Bodenmiller, Bernd , Licon, Katherine , Copeland, Wilbert , Shales, Michael , Fiedler, Dorothea , Dutkowski, Janusz , Guénolé, Aude , van Attikum, Haico , Shokat, Kevan M , Kolodner, Richard D , Huh, Won-Ki , Aebersold, Ruedi , Keogh, Michael-Christopher , Krogan, Nevan J and Ideker, Trey
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Although cellular behaviors are dynamic, the networks that govern these behaviors have been mapped primarily as static snapshots. Using an approach called differential epistasis mapping, we have discovered widespread changes in genetic interaction among yeast kinases, phosphatases, and transcription factors as the cell responds to DNA damage. Diffe...
Alternative Titles
Full title
Rewiring of Genetic Networks in Response to DNA Damage
Authors, Artists and Contributors
Author / Creator
Mehta, Monika
Kuo, Dwight
Sung, Min-Kyung
Chuang, Ryan
Jaehnig, Eric J
Bodenmiller, Bernd
Licon, Katherine
Copeland, Wilbert
Shales, Michael
Fiedler, Dorothea
Dutkowski, Janusz
Guénolé, Aude
van Attikum, Haico
Shokat, Kevan M
Kolodner, Richard D
Huh, Won-Ki
Aebersold, Ruedi
Keogh, Michael-Christopher
Krogan, Nevan J
Ideker, Trey
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3006187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3006187
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1195618
