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ArticlesPeer ReviewedFull Text
Features and regulation of non-enzymatic post-translational modifications
Author / Creator:Harmel, Robert ; Fiedler, Dorothea
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2018-02, Vol.14 (3), p.244-252
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Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health
Author / Creator:Bui, Thi Phuong Nam ; Mannerås-Holm, Louise ; Puschmann, Robert ; Wu, Hao ; Troise, Antonio Dario ; Nijsse, Bart ; Boeren, Sjef ; Bäckhed, Fredrik ; Fiedler, Dorothea ; deVos, Willem M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.4798-4798, Article 4798
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Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis
Author / Creator:Ried, Martina K. ; Wild, Rebekka ; Zhu, Jinsheng ; Pipercevic, Joka ; Sturm, Kristina ; Broger, Larissa ; Harmel, Robert K. ; Abriata, Luciano A. ; Hothorn, Ludwig A. ; Fiedler, Dorothea ; Hiller, Sebastian ; Hothorn, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.384-384, Article 384
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Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry
Author / Creator:Qiu, Danye ; Wilson, Miranda S. ; Eisenbeis, Verena B. ; Harmel, Robert K. ; Riemer, Esther ; Haas, Thomas M. ; Wittwer, Christopher ; Jork, Nikolaus ; Gu, Chunfang ; Shears, Stephen B. ; Schaaf, Gabriel ; Kammerer, Bernd ; Fiedler, Dorothea ; Saiardi, Adolfo ; Jessen, Henning J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-11, Vol.11 (1), p.6035-12, Article 6035
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Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis
Author / Creator:Zhu, Jinsheng ; Lau, Kelvin ; Puschmann, Robert ; Harmel, Robert K ; Zhang, Youjun ; Pries, Verena ; Gaugler, Philipp ; Broger, Larissa ; Dutta, Amit K ; Jessen, Henning J ; Schaaf, Gabriel ; Fernie, Alisdair R ; Hothorn, Ludwig A ; Fiedler, Dorothea ; Hothorn, Michael
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2019-08, Vol.8
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Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction
Author / Creator:Pipercevic, Joka ; Kohl, Bastian ; Gerasimaite, Ruta ; Comte-Miserez, Véronique ; Hostachy, Sarah ; Müntener, Thomas ; Agustoni, Elia ; Jessen, Henning Jacob ; Fiedler, Dorothea ; Mayer, Andreas ; Hiller, Sebastian
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-05, Vol.14 (1), p.2645-12, Article 2645
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Inositol pyrophosphate catabolism by three families of phosphatases regulates plant growth and development
Author / Creator:Laurent, Florian ; Bartsch, Simon M. ; Shukla, Anuj ; Rico-Resendiz, Felix ; Couto, Daniel ; Fuchs, Christelle ; Nicolet, Joël ; Loubéry, Sylvain ; Jessen, Henning J. ; Fiedler, Dorothea ; Hothorn, Michael
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2024-11, Vol.20 (11), p.e1011468
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Rewiring of Genetic Networks in Response to DNA Damage
Author / Creator:Bandyopadhyay, Sourav ; Mehta, Monika ; Kuo, Dwight ; Sung, Min-Kyung ; Chuang, Ryan ; Jaehnig, Eric J ; Bodenmiller, Bernd ; Licon, Katherine ; Copeland, Wilbert ; Shales, Michael ; Fiedler, Dorothea ; Dutkowski, Janusz ; Guénolé, Aude ; van Attikum, Haico ; Shokat, Kevan M ; Kolodner, Richard D ; Huh, Won-Ki ; Aebersold, Ruedi ; Keogh, Michael-Christopher ; Krogan, Nevan J ; Ideker, Trey
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6009), p.1385-1389
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An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Author / Creator:Aguirre, Tim ; Dornan, Gillian L ; Hostachy, Sarah ; Neuenschwander, Martin ; Seyffarth, Carola ; Haucke, Volker ; Schütz, Anja ; von Kries, Jens Peter ; Fiedler, Dorothea
Publisher:Cambridge: eLife Sciences Publications Ltd
Journal title:eLife, 2023-10, Vol.12
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A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis
Author / Creator:Raia, Pierre ; Lee, Kitaik ; Bartsch, Simon M. ; Rico-Resendiz, Felix ; Portugal-Calisto, Daniela ; Vadas, Oscar ; Panse, Vikram Govind ; Fiedler, Dorothea ; Hothorn, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1753-20, Article 1753
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One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP8 Occurs under Cytosolic Conditions
Author / Creator:Kurz, Leonie ; Schmieder, Peter ; Veiga, Nicolás ; Fiedler, Dorothea
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-04, Vol.13 (4), p.645
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ArticlesPeer ReviewedFull Text
Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species
Author / Creator:Beltrao, Pedro ; Trinidad, Jonathan C. ; Fiedler, Dorothea ; Roguev, Assen ; Lim, Wendell A. ; Shokat, Kevan M. ; Burlingame, Alma L. ; Krogan, Nevan J.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2009-06, Vol.7 (6), p.e1000134-e1000134
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ArticlesPeer ReviewedFull Text
Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP7
Author / Creator:Sahu, Soumyadip ; Gordon, Jacob ; Gu, Chunfang ; Sobhany, Mack ; Fiedler, Dorothea ; Stanley, Robin E. ; Shears, Stephen B.
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-01, Vol.13 (1), p.153
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Differential genetic interactions of yeast stress response MAPK pathways
Author / Creator:Martin, Humberto ; Shales, Michael ; Fernandez‐Piñar, Pablo ; Wei, Ping ; Molina, Maria ; Fiedler, Dorothea ; Shokat, Kevan M ; Beltrao, Pedro ; Lim, Wendell ; Krogan, Nevan J
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2015-04, Vol.11 (4), p.800-n/a
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Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe
Author / Creator:Kuenzel, Natascha Andrea ; Alcázar-Román, Abel R. ; Saiardi, Adolfo ; Bartsch, Simon M. ; Daunaraviciute, Sarune ; Fiedler, Dorothea ; Fleig, Ursula
Publisher:Switzerland: MDPI AG
Journal title:Journal of fungi (Basel), 2022-09, Vol.8 (9), p.933
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Encapsulation and characterization of proton-bound amine homodimers in a water-soluble, self-assembled supramolecular host
Author / Creator:Pluth, Michael D ; Fiedler, Dorothea ; Mugridge, Jeffrey S ; Bergman, Robert G ; Raymond, Kenneth N
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10438-10443
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Correction: Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species
Author / Creator:Beltrao, Pedro ; Trinidad, Jonathan C. ; Fiedler, Dorothea ; Roguev, Assen ; Lim, Wendell A. ; Shokat, Kevan M. ; Burlingame, Alma L. ; Krogan, Nevan J.
Publisher:San Francisco, USA: Public Library of Science
Journal title:PLoS biology, 2009-11, Vol.7 (11)
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Control of XPR1-dependent cellular phosphate efflux by InsP₈ is an exemplar for functionally-exclusive inositol pyrophosphate signaling
Author / Creator:Li, Xingyao ; Gu, Chunfang ; Hostachy, Sarah ; Sahu, Soumyadip ; Wittwer, Christopher ; Jessen, Henning J. ; Fiedler, Dorothea ; Wang, Huanchen ; Shears, Stephen B.
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (7), p.3568-3574
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Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms
Author / Creator:Wu, Mingxuan ; Chong, Lucy S. ; Perlman, David H. ; Resnick, Adam C. ; Fiedler, Dorothea
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (44), p.E6757-E6765
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Inhibitor hijacking of Akt activation
Author / Creator:Okuzumi, Tatsuya ; Fiedler, Dorothea ; Zhang, Chao ; Gray, Daniel C ; Aizenstein, Brian ; Hoffman, Randy ; Shokat, Kevan M
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2009-07, Vol.5 (7), p.484-493
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Showing 1 to 20 of 41 results

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Features and regulation of non-enzymatic post-translational modifications

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Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health

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Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis

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Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

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Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis

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Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction

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Inositol pyrophosphate catabolism by three families of phosphatases regulates plant growth and development

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Rewiring of Genetic Networks in Response to DNA Damage

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An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor

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A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis

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One Scaffold, Two Conformations: The Ring-Flip of the Messenger InsP8 Occurs under Cytosolic Conditions

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Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species

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Nucleolar Architecture Is Modulated by a Small Molecule, the Inositol Pyrophosphate 5-InsP7

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Differential genetic interactions of yeast stress response MAPK pathways

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Inositol Pyrophosphate-Controlled Kinetochore Architecture and Mitotic Entry in S. pombe

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Encapsulation and characterization of proton-bound amine homodimers in a water-soluble, self-assembled supramolecular host

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Correction: Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species

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Control of XPR1-dependent cellular phosphate efflux by InsP₈ is an exemplar for functionally-exclusive inositol pyrophosphate signaling

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Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms

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Inhibitor hijacking of Akt activation

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